Inflammatory and Immunological parameters in adults with Down syndrome

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Vocal Parameters of Adults with Down Syndrome in Zahedan /Iran

Background & Aims: Previous studies have indicated significant differences in vocal parameters between children with Down syndrome and normal children, but there are challenges about these differences. In this study vocal parameters and Maximum Phonation Time (MPT) in adults with Down syndrome have been investigated. Method: This cross-sectional and analytic study was performed on 22 adults wit...

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Voice parameters in children with Down syndrome.

Down syndrome (DS) is the most frequent chromosomal disorder. Commonly, individuals with DS have difficulties with speech and show an unusual quality in the voice. Their phenotypic characteristics include general hypotonia and maxillary hypoplasia with relative macroglossia, and these contribute to particular acoustic alterations. Subjective perceptual and acoustic assessments of the voice (Pra...

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Hip disease in adults with Down syndrome.

The life expectancy of patients with Down syndrome has increased significantly in recent years. Hip abnormalities occur in children with this syndrome but little is known about their natural history in later life. In 65 adults with Down syndrome we found hip abnormalities in 28%, and this was statistically correlated with walking ability. A subgroup of 18 patients was followed by serial examina...

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Ophthalmic Disorders in Adults with Down Syndrome

A myriad of ophthalmic disorders is associated with the phenotype of Down syndrome including strabismus, cataracts, and refractive errors potentially resulting in significant visual impairment. Ophthalmic sequelae have been extensively studied in children and adolescents with Down syndrome but less often in older adults. In-depth review of medical records of older adults with Down syndrome indi...

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Alzheimer's Disease in Adults with Down Syndrome.

S TO C K P H O TO . P O S E D B Y M O D E L. Adults with Down syndrome (DS) are at increased risk for Alzheimer’s disease (AD), with dementia incidence rising dramatically beginning in their late 40s. This population is expanding rapidly due to improvements in clinical practice and positive changes in public policy occurring over recent decades. Early recognition of AD will be ever more importa...

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ژورنال

عنوان ژورنال: Immunity & Ageing

سال: 2011

ISSN: 1742-4933

DOI: 10.1186/1742-4933-8-4